Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-20 |
filingDate |
2003-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2006-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c53bd0b080764e5d1a3543ed33034ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6604ccf7df0f3647256d702c22f7a32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_108d076a51e2c75d1f7480ff04c8912f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f55ee4b7e73843e328e88343050c6a2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df8936dff77242600b4b53ce0b5c6cfe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63c36bd41049c89936a457c1687263a4 |
publicationDate |
2006-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-7026486-B2 |
titleOfInvention |
Process for production cilostazol |
abstract |
The present invention provides a process for producing cilostazol [I] in a high yield and a high purity, by reacting a carbostyril derivative [II] with a tetrazole derivative [III] in the presence of an inorganic basic compound in a solvent of water, wherein water is used in an amount of 3 to 7-fold weight to that of the carbostyril derivative [II] and the inorganic basic compound is used in an amount of 1 to 6 mol per mol of the carbostyril derivative [II]. The process of the present invention is the improved and environment-friendly process for producing cilostazol being useful for pharmaceuticals |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005222202-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7825251-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005101631-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007282108-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004024017-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7399864-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7524960-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011165236-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006100437-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008075785-A1 |
priorityDate |
2002-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |