http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5645414-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12
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filingDate 1979-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93e3e30d63b43bd232eec3cef7e1aef0
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publicationDate 1981-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S5645414-A
titleOfInvention Phosphodiesterase inhibitor
abstract NEW MATERIAL:A tetrazolylpropoxycarbostyryl derivative of formula I (R is lower alkyl or cycloalkyl). n EXAMPLE: 6-[3-(1-cyclohexyltetrazol-5-yl)propoxy]carbostyryl. n USE: A phosphodiesterase-inhibiting, circulation improving and hypotensive agent having remedying activity to cancer and mental disorder and remedying and preventive activities to bronchial asthma and allergic asthma. Low toxicity and side effects. n PROCESS: The compound of formula I is prepared, e.g. by the dehydrohalogenation reaction of a 6-hydroxycarbostyryl of formula II (X is halogen) and a tetrazole derivative of formula III. n COPYRIGHT: (C)1981,JPO&Japio
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Total number of triples: 29.