| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c902faf6ae746c51fc8010672fc22894 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D273-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D273-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate |
2002-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0b55169015b54dba8f87359ca59cc2b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_029f5a0b9eda8feab0d0a5d45a766259
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcedf09cc39b0d6c9ee22b5ad8f9c3a2 |
| publicationDate |
2005-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6969709-B2 |
| titleOfInvention |
Macrocycles useful in the treatment of Alzheimer's disease |
| abstract |
The present invention are macrocycles of the formula (IX): n n nfor treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010022500-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009170878-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009029960-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008132477-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8008250-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8039455-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008214526-A1 |
| priorityDate |
2001-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |