| abstract |
Polyoxometalate compounds which exhibit anti-retroviral activity are disclosed. Compounds with anti-retroviral activity include those having the following general molecular formulas:n nM 7 PW 11 O 39 n nM 8 SiW 11 O 39 n nM 9 HSiW 9 O 34 n nM 8 HPW 9 O 34 n nM 10 (TM) 4 (PW 9 O 34 ) 2 n nM 16 (TM) 4 (P 2 W 15 O 56 ) 2 n nM 14 [NaP 5 W 30 O 110 ]n nM 12 (TM) 3 (PW 9 O 34 ) 2 n nM 6 P 2 W 18 O 62 n wherein M is an alkali metal, NH 4 + or other common monocation or soluble dication, or any combination of the above provided adequate water solubility is exhibited, or histidinium ion, argininium ion, or lysinium ion or any dication of a dipeptide or oligopeptide with 2 protonated basic amino acid residues, or any combination of these monocations or dications with each other or with any common inorganic cation, and TM is a divalent transition metal ion, such as Mn, Fe, Co, Ni, Cu and Zn. |