| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 |
| filingDate |
2001-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1dc71fb6fe11c2e7b91ce6493abe1e3 |
| publicationDate |
2005-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6878832-B2 |
| titleOfInvention |
Isolation of taxanes |
| abstract |
An improved method for the isolation of taxanes of high purity from the crude extract of naturally occurring Taxus canadensis which comprises the steps of: a) filtering the crude extract by liquid column chromatography; b) enriching the taxanes obtained from step a) by precipitation and crystallization; and c) dissolving the taxanes extract in a polar organic solvent mixture comprising an alcohol and a non-alcohol solvent, which solution is then subjected to further separation by liquid column chromatography, and isolating substantially pure paclitaxel from cephalomannine; and all solvent mixtures used may be collected, purified and recycled without separation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8002987-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7919108-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7880022-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011153007-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007212394-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7875284-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008286325-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007112207-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008290028-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8147540-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008020013-A1 |
| priorityDate |
2000-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |