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filingDate 2006-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2007-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-2007112207-A1
titleOfInvention Method for separation and purification of 13-dehydroxybaccatin iii and 10-deacetylpaclitaxel from taxans-containing materials
abstract This invention is directed to a method for efficiently separating and purifying 13-dehydroxybaccatin III and 10-deacetylpaclitaxel with a high purity of 90% or higher purity, preferably 99.5% or higher purity, from taxane-containing materials such as Taxus species, and the thusly obtained highly pure 13-dehydroxybaccatin III and 10-deacetylpaclitaxel can be used as semi-synthetic precursors of paclitaxel and/or docetaxel that are anticancer agents.
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