http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6872526-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f60f7884c3b8246b6939e7ca6e98d356 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1037 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate | 2001-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2005-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2adfc4fe0e9faca4b77f53138c1241ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a7011c82a526e380d4d141616fd6c00 |
publicationDate | 2005-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-6872526-B2 |
titleOfInvention | High throughput screening for novel Bioactivities |
abstract | Disclosed is a process for identifying clones having a specified activity of interest, which process comprises (i) generating one or more expression libraries derived from nucleic acid directly isolated from the environment; and (ii) screening said libraries utilizing a fluorescence activated cell sorter to identify said clones. More particularly, this is a process for identifying clones having a specified activity of interest by (i) generating one or more expression libraries derived from nucleic acid directly or indirectly isolated from the environment; (ii) exposing said libraries to a particular substrate or substrates of interest; and (iii) screening said exposed libraries utilizing a fluorescence activated cell sorter to identify clones which react with the substrate or substrates. Also provided is a process for identifying clones having a specified activity of interest by (i) generating one or more expression libraries derived from nucleic acid directly or indirectly isolated from the environment; and (ii) screening said exposed libraries utilizing an assay requiring co-encapsulation, a binding event or the covalent modification of a target, and a fluorescence activated cell sorter to identify positive clones. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10729731-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8071054-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11633435-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8263387-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129906-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10828356-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008147530-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10449237-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9616114-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011003303-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11180535-B1 |
priorityDate | 1997-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 204.