abstract |
The present invention is directed towards novel compounds that are effective inhibitors of integrins, particularly α IIb β 3 or α v integrins such as α v β 3 and α v β 5 . One embodiment of the present invention comprises a compound of formula (I) or formula (II) or a pharmaceutically acceptable salt, solvate, or metabolic precursor thereof. R1, R2, R3, and R4 are defined herein. |