| abstract |
A compound for treating spinal muscular atrophy by bringing into contact with human cells and promoting the insertion of exon 7 of SMN2 into mRNA transcribed from the SMN2 gene, and containing the compound Providing a pharmaceutical composition. A compound represented by the following formula and a pharmaceutical composition containing the compound. [R1 is piperazinyl, morpholinyl, 1,4-diazepanyl, etc .; R2 is phenyl; Ra is H, halogen, or C1-8 alkyl; Rb is H, halogen, C1-8 alkyl, or C1-8 alkoxy Rc is H, halogen, or C1-8 alkyl] |