| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-52 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-18 |
| filingDate |
1997-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94f18b34b02258bf878dd7d218ea89cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a94849a47844853da040a0efddeb1aa6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db2b9a8f5c63e244d8ef0d649fd3d4f2 |
| publicationDate |
2002-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6485942-B1 |
| titleOfInvention |
Variants of vascular endothelial cell growth factor having altered pharmacological properties, and recombinant methods of production |
| abstract |
Described herein are vascular endothelial cell growth factor (VEGF) variants having modifications in the C-terminus heparin binding domain. The variants exhibit reduced clearance rates for systemic administration generally at lower doses compared with native VEGF thus providing variants having longer availability for therapeutic effect. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9321832-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010005850-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009118208-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006257406-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7893243-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7893244-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004224885-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7078382-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7696320-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9078860-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007093651-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7355019-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010216702-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8877186-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10766941-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005221431-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004219643-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10544200-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009203894-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7807778-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011124710-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008312410-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2093235-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8759285-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002193288-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006106203-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009155283-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009259026-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10457713-B2 |
| priorityDate |
1997-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |