| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5e95156255d5fe8b2923c544786e176 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0278
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 |
| filingDate |
1998-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2e0261f3864b9dd5ff107888ce00509 |
| publicationDate |
2002-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6448470-B1 |
| titleOfInvention |
Transgenic COL2A1-null mice expressing human COL2A1 |
| abstract |
Transgenic animals which express human collagen gene and have an inactivated endogenous collagen gene are provided. Compositions comprising humanized chondrocytes isolated from these transgenic animals are also provided. In addition, methods of screening potential therapeutics for cartilage related disorders in these animals are provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006051794-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020127533-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113785068-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7718366-B2 |
| priorityDate |
1997-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |