| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0647
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5403
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-08 |
| filingDate |
1996-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_857bf9807e16b46bb4124fedb7dcc762
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_294a8c7c1df754c72b7ad84d17d153a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9ba15003f2a01f879a701971b631502
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_320e595d8730e120eba8a27eebc08e1c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a40da629ea3695a5c8e2a2e471f18045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01bb0865614e9f3ef09cf13d5586c94d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf0091bef5c801a7578c974afe18c647
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_534068ca97f1e06acbcbb48ee206827b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ee882044f98a927f2ac9216a0fc8051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d0ba55dcd600960118d80a9a97648a1 |
| publicationDate |
2002-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6413509-B1 |
| titleOfInvention |
Methods of ex-vivo expansion of hematopoietic cells using interleukin-3 mutant polypeptides with other hematopoietic growth factors |
| abstract |
The present invention relates to methods of ex-vivo expansion of hematopoietic cells by culturing hematopoietic cells in a growth medium comprising a variant of human interleukin-3 (hIL-3), which contains multiple amino acid substitutions and which may have portions of the native hIL-3 molecule deleted, and a hematopoietic growth factor. The present invention also relates to the ex-vivo expansion of hematopoietic cells for gene therapy. Additionally, the present invention relates to the use of the expanded hematopoietic cells for treating patients having a hematopoietic disorder. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005054054-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007196911-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008003681-A1 |
| priorityDate |
1992-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |