| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1394e66eb648f9bf0a1f5507fe25b67b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dfd617dc43a4c986d2dd81e4cb39d9dd |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-22 |
| filingDate |
1995-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2baefdde15d6987103b2ed74d083ae92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a3e4d7a87ceb091bff3a050a973711b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdbbc96a94c5c86affa77fa0d68ebd7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c4e8a300fde9ca60d41d888dc371548 |
| publicationDate |
2002-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6407115-B1 |
| titleOfInvention |
Hexa-cyclic compound |
| abstract |
Accordingly, an object of this invention is to provide a hexa-cyclic compound represented by the following general formula:wherein R1 and R2 individually represent a hydrogen atom, a hydroxyl group, a C1-6 alkyl group ("C1-6 alkyl group means an alkyl group having 1 to 6 carbon atoms. Hereinafter defined in the same manner.)The present inventors have conducted extensive studies for the purpose of obtaining camptothecin derivatives with more excellent activity and higher safety, as well as excellent characteristics required for a drug to be administered, and found that hexa-cyclic compounds obtained by the addition of a water-soluble ring to camptothecin had characteristics superior to camptothecin. This finding has led to the completion of this invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11446292-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022161479-A1 |
| priorityDate |
1991-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |