| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27155ed29f9b0bfa281f4b21b26d709a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70521 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 |
| filingDate |
1999-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2113f441880aec2f0029e2e63253e1d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5882a7a6c4f8e284f01e117c7ed11783
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b23ec7c8d33eb13d8aed805e2f618c94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7eed4e81fc1f61943b181b022927b88 |
| publicationDate |
2002-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6337316-B1 |
| titleOfInvention |
Pharmaceutical compositions thereof, and methods of using same |
| abstract |
The present invention relates to peptidomimetics capable of inhibiting CD28 and/or CTLA-4 interaction with CD80 (B7-1) and CD86 (B7-2) and having a core amino acid sequence, LeuMetTyrProProProTyrTyr, corresponding to residues 2 to 9 of SEQ ID NO:1. The present invention also relates to pharmaceutical compositions and a method of treating pathologies and disorders which are improved by inhibition of CD28 and/or CTLA-4 interaction with CD80 and CD86. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9546207-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010195797-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10927154-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8535672-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2899277-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009007853-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004087196-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005191296-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9221885-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6852847-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006524233-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4708333-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006075968-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2004226566-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012072806-A1 |
| priorityDate |
1997-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |