| abstract |
Compounds of formula (I) and pharmaceutically acceptable salts thereof: n where n R 1 is hydrogen, C 1-6 alkyl optionally substituted by hydroxy or C 1-4 alkoxy, or C 1-6 alkylphenyl; n R 2 is hydrogen or up to three substituents selected from halogen, NO 2 , CN, N 3 , C 1-6 alkylO-, C 1-6 alkylS-, C 1-6 alkyl, C 3-6 cycloalkyl, n C 3-6 cycloalkyl-C 1-4 alkyl-, C 1-6 alkenyl, C 1-6 alkynyl, CF 3 , CF 3 O, CF 3 CO—, C 1-6 alkylCO-, C 3-6 cycloalkylCO-, n C 3-6 cycloalkyl-C 1-4 alkylCO-, phenyl, phenoxy, benzyloxy, benzoyl, phenyl-C 1-4 alkyl-, n or —NR 3 R 4 where n R 3 is hydrogen or C 1-4 alkyl, and n R 4 is hydrogen, C 1-4 alkyl, —CHO, n —CO 2 C 1-4 alkyl or —COC 1-4 alkyl; n or two R 2 groups form a saturated carbocyclic ring optionally interrupted by oxygen; n and X is selected from hydrogen, halogen, cyano, alkyl and alkoxy; n are useful in the treatment and prophylaxis of inter alia epilepsy. |