| abstract |
Compounds having the following formula I, and pharmaceutically acceptable salts thereof, including dual inhibitors of ACE and NEP and selective ACE inhibitors:wherein:Y1 and Y2 are each independently hydrogen, alkyl, aryl, halogen, or alkoxy;X is O or S(O)t;A ist is zero, one or two;m and n are independently zero or one;and wherein R, R5, R5a, R5b, R6, R7, R11, q and r are defined herein. |