| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cdfcf975092110ad153f8af470345bf6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a722744e77c81c5f5cf415087e2ee92b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6897
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
1998-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2001-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab265019700bfff2418cf3541f61573b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69c856af9b5e4c2bc2c77356737e818a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e69cee0d0124106a715dbf1aef78afa |
| publicationDate |
2001-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6200760-B1 |
| titleOfInvention |
Method of screening agents as candidates for drugs or sources of drugs |
| abstract |
Cells are transfected with a construct containing transcriptional promoter element(s) that have been implicated in carcinogenesis or inflammation ligated to a reporter gene. Determination of inhibition of activation of said promoter element(s) by putative agent indicates the agent is a candidate as a drug or source of a drug for prophylaxis or treatment of cancer or inflammation. The method has particular application to screening agents as candidates for drugs or sources of drugs for prophylaxis or treatment of human disorders caused or mediated by cyclooxygenase-2 and/or matrix metalloproteinases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005031537-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006014218-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004152126-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010099108-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2021499-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008220983-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10663455-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009005385-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006014218-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9663823-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002086842-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004241755-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011065100-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010221346-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007161031-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2021499-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8815779-B2 |
| priorityDate |
1997-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |