| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_129e393582e6bdf4029baf2206522f45 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-00 |
| filingDate |
1999-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_154d5fc002b9989d3f7e15e08e45c30c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a343d91fa41f6487fb9f4adfc22b8e48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a19dccdc2ebd19efa640009cdf6a672
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80fceb672bc9678cce55792e776c08d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ae6dc4e27fa0ae62a8233a1c2935d56 |
| publicationDate |
2000-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6147084-A |
| titleOfInvention |
Brain cell protective agent |
| abstract |
The present invention relates to a novel brain cell protective agent having for its active ingredient a morphinan derivative represented with Compound 1 ##STR1## or pharmacologically acceptable acid addition salt thereof. The compounds used in the present invention were found to have excellent defensive effects against brain nerve cell necrosis in both in vitro and in vivo pharmacological evaluations, and can be used as useful preventive and therapeutic agents of ischemic brain disorders, brain nerve cell disorders and dementia. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8637539-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9725457-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014255308-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11046692-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11214577-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10150775-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006094741-A1 |
| priorityDate |
1993-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |