| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_785ac2b35073f5a6d251678e6fb31b6f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3527
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3521
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-322 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate |
1998-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bd94ed5c75d5405b9d2488bae6f399c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0792f0d22dfe7322a82bc3251e8e626d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3631483bc67e3a86b7fabc4a3a52b063 |
| publicationDate |
2000-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6117848-A |
| titleOfInvention |
Antisense oligonucleotide inhibition of ras |
| abstract |
Compositions and methods are provided for the modulation of ras expression. Oligonucleotides are provided which are targeted to nucleic acids encoding human ras. Oligonucleotides specifically hybridizable with mRNA encoding human H-ras, Ki-ras and N-ras are provided. Such oligonucleotides can be used for therapeutics and diagnostics as well as for research purposes. Methods are also disclosed for modulating ras gene expression in cells and tissues using the oligonucleotides provided, and for specific modulation of expression of activated ras. Methods for diagnosis, detection and treatment of conditions associated with ras are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9493845-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7067495-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8173428-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009181914-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011003887-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7713738-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002165196-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013347133-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9476870-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7741309-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8026355-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002119570-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010222231-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003054354-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010292311-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009023599-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9394539-B1 |
| priorityDate |
1992-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |