| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 |
| filingDate |
1999-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49705560e8ef236d04e26abc4fc6c4d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed73aa34c74a2c44be278f2e4058f91b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ed522bf92b01086f3f478736ff6039f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aebea4b8d6a1325286950e572dfe3af0 |
| publicationDate |
2000-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6066658-A |
| titleOfInvention |
Condensed 4,5,6,7-tetrahydrobenzo[C]thiophenes as enhancer for cell differentiation induction factor action |
| abstract |
A compound represented by the formula: wherein X represents a sulfur atom or an oxygen atom; Y represents an optionally oxidized sulfur atom or an oxygen atom; Z represents a bond or a divalent hydrocarbon group; R1 represents an optionally substituted hydrocarbon group; R2 represents an optionally amidated or esterified carboxyl group; ring A represents an optionally substituted aromatic 5-membered heterocyclic ring; or a salt thereof. A compound of the above formula possesses cell differentiation inducing factor action-enhancing activity and anti-matrix metalloprotease activity and that is useful in the prevention and treatment of bone diseases such as osteoporosis, bone fractures, osteoarthritis and rheumatoid arthritis, arteriosclerosis, cancer metastasis, and diseases based on nerve degeneration. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006173009-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02092606-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02083083-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8224945-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8697139-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017189553-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009172158-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7101905-B2 |
| priorityDate |
1996-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |