| abstract |
PCT No. PCT/US95/00298 Sec. 371 Date Jan. 7, 1997 Sec. 102(e) Date Jan. 7, 1997 PCT Filed Jan. 11, 1995 PCT Pub. No. WO95/18830 PCT Pub. Date Jul. 13, 1995This invention relates to novel mutants of the first Kunitz domain (K1) of the human lipoprotein-associated coagulation inhibitor (LACI) which inhibit plasmin. The invention also relates to other modified Kunitz domains that inhibit plasmin and to other plasmin inhibitors. |