Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4712 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
1995-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1999-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6096d6768df675a3c612d71f2aff163d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19e2709d622482cb7e458a4a7dcefbdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08cab5bd6fe88ac6c08145d2f44cceca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4085fa22d22c09c849ff4041597b3dbd |
publicationDate |
1999-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5989540-A |
titleOfInvention |
Modified adeno-associated virus vector capable of expression from a novel promoter |
abstract |
Described herein are constructions of recombinant DNA comprising modified adeno-associated virus (AAV) DNA sequences capable of functioning as a eukaryotic expression vector for expressing foreign DNA sequences using a novel transcription promoter comprising the termini of AAV DNA. It is shown that expression of a test reporter gene can be obtained from this vector in mammalian cells. It is further shown that this combination of vector and promoter can be used to introduce and express a human gene and correct a genetic defect in human cells resulting from malfunction of the mutant endogenous gene. Further, the vector can be used to correct the genetic defect by expressing a modified version of the human gene consisting of a fusion of part of the said gene and a synthetic sequence contained in the vector. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11542506-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6294379-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10577627-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11603542-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11752181-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003175974-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8093054-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003219735-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002192826-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10597660-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11299751-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2181704-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10584337-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6936466-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11198873-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11512327-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6596535-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11326182-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11697825-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7846729-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7060497-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10570395-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7125717-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007087433-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11759506-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11497576-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0166782-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11027000-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10920227-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10335466-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6924128-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11434502-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6893865-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10369193-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7785888-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005148076-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6383814-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11298041-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11193129-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008206197-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9415119-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6207457-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003191233-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10983110-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006019382-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011104117-A1 |
priorityDate |
1992-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |