| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c5731aa4881af0699108372a8a9e1e48 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-246
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-126
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-128
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0683
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0677 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate |
1996-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fa86a3be6bd633fd51a7110157c9e2c |
| publicationDate |
1999-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5958404-A |
| titleOfInvention |
Treatment methods for disease using co-localized cells and Sertoli cells obtained from a cell line |
| abstract |
A method of treating a disease is provided that results from a deficiency of a biological factor which comprises administering to a mammal Sertoli cells and cells that produce the biological factor. A method of treating diabetes mellitus is carried out by transplanting pancreatic islet of Langerhans cells in conjunction with Sertoli cells to create an immunologically privileged site. A method of creating an immunologically privileged site and providing cell stimulatory factors in a mammal for transplants is also carried out. A method of co-localizing islet cells with Sertoli cells and the use of the co-localized product for treating diabetes mellitus is further provided. Further described is a method of creating systemic tolerance to foreign antigens. A method of enhancing the viability, maturation, proliferation of functional capacity of cells in tissue culture is also provided. In addition, a pharmaceutical composition comprising Sertoli cells and cells that produce a biological factor is provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002150953-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10034963-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009191167-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02094987-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02094987-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015283321-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11730860-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7399751-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10532128-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009028833-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008145348-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008274090-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9011899-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6872569-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004197374-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6649160-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004197375-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009162331-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7629308-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1466632-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002192200-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003027329-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8263068-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-100404074-C
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6703017-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008233089-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9707336-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004062753-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6790441-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10207026-B2 |
| priorityDate |
1994-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |