| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3513
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-22055 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
1997-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e3bff4325fdd1c78488c05e7b0d5aa9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76c568d95476dab382e267498c609720 |
| publicationDate |
1999-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5929042-A |
| titleOfInvention |
Antisense compounds which prevent cell death and uses thereof |
| abstract |
The present invention provides for an antisense oligonucleotide having the sequence 5'GCTCGGCGCCGCCATTTCCAG3'(SEQ ID NO:1). The invention also provides for an antisense oligonucleotide having the sequence 5'GTCAGCGGCCATCAGCTT3'(SEQ ID NO:2). The present invention further provides for a method for treating a neurodegenerative disorder in a subject which comprises administering to the subject a compound in an amount effective to inhibit neuronal cell death and thus treat the neurodegenerative disorder in the subject, which compound comprises the oligonucleotide 5'GCTCGGCGCCGCCATTTCCAG3' (SEQ ID NO:1) and a delivery agent. The present invention provides for a method of inhibiting trophic factor withdrawal mediated death of a cell which comprises contacting the cell with an amount of the oligonucleotide 5'GCTCGGCGCCGCCATTTCCAG3' (SEQ ID NO:1) effective to inhibit death of the cell. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009044392-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6844324-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8614309-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10036025-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9446062-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004147027-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006178297-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8431692-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011142917-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008021107-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7247438-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005020530-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10626398-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9796978-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006100134-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0025798-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9777275-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10196640-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004224913-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003092659-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8524680-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011112168-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2371958-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9089591-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10106793-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007218121-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8815821-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9592250-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7754678-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7223856-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7414034-B2 |
| priorityDate |
1997-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |