abstract |
A compound of formula (I) <IMAGE> (I) wherein R1 is selected from the group consisting of 2-thienyl, 2-furyl, 2-pyrrolyl, 1-methyl-2-pyrrolyl, 2-amino-1-thiazolyl and 5-isothiazolyl; R2 is selected from the group consisting of: <IMAGE> (a) <IMAGE> (b) <IMAGE> (c) <IMAGE> (d) <IMAGE> (e) <IMAGE> (f) <IMAGE> (g) and M is hydrogen or a pharmaceutically acceptable cation; wherein the oxyimino fragment (=N-OR2) in formula (I) is in the 'anti' orientation. |