Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2243a54fef78f99c39546c86983fb218 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2658d45a8e9c71b9598e2bf83242bab3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2795-10022 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-22 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-01 |
filingDate |
1997-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1998-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1402d2420cceb221e04b84d603da4e57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2adb07de5f958af0056342415646d52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfd2ca644ee2b16972f1c8c802348a0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd790b722e63fed98f8d10cfb9266255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_946b595502487bafee22aeae36135927 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1630a85eba0b3d682b799e71ed05749e |
publicationDate |
1998-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5747287-A |
titleOfInvention |
Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis |
abstract |
The present invention relates, in general, to a method for the high level expression of the outer membrane protein meningococcal group B porin proteins and fusion proteins thereof. In particular, the present invention relates to a method of expressing the outer membrane protein meningococcal group B porin proteins in E. coli wherein the meningococcal group B porin proteins and fusion proteins thereof comprise more than 2% of the total protein expressed in E. coli. The invention also relates to a method of purification and refolding of the meningococcal group B porin proteins and fusion proteins thereof and to their use in vaccines. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9903501-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11180535-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9616114-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004197845-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7118757-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6451317-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10729731-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10828356-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112062820-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112062820-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021144473-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129906-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11633435-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6153406-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10449237-B1 |
priorityDate |
1995-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |