abstract |
PCT No. PCT/JP95/00407 Sec. 371 Date Sep. 9, 1996 Sec. 102(e) Date Sep. 9, 1996 PCT Filed Mar. 10, 1995 PCT Pub. No. WO95/24412 PCT Pub. Date Sep. 14, 1995Novel anthracycline derivatives have now been produced, which exhibit higher antitumor activities and lower toxicities than those of daunomycin, adriamycin etc. that have been clinically used as anticancer agents. That is, a daunomycinone or adriamycinone derivative represented by the general formula (I): <IMAGE> (I) wherein R is a hydrogen atom or a hydroxyl group. |