abstract |
PCT No. PCT/US93/11225 Sec. 371 Date Sep. 15, 1995 Sec. 102(e) Date Sep. 15, 1995 PCT Filed Nov. 18, 1993 PCT Pub. No. WO94/11004 PCT Pub. Date May 26, 1994Invented are 17 alpha and 17 beta -substituted acyl-3-carboxy-3,5-diene analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5- alpha -reductase. Also invented are intermediates and processes used in preparing these compounds. |