abstract |
Perfluoroalkylated amphiphilic phosphorus compounds, corresponding to the formulae: <IMAGE> Ia <IMAGE> Ib wherein V is O or S; R1, R2 and R3 are H or substituted or unsubstituted perfluoroalkylated or hydrocarbon radicals; provided that R1, R2 or R3 is a perfluoroalkylated radical; and Y and Z are radicals which can bear a part derived from a sugar, a polyol, or a hydrophilic polymer such as polyethyleneglycol, a perfluoroalkylated part or a part derived from a pharmaceutically active molecule, and method for their preparation and use. These compounds can be included in preparations, emulsions, dispersions, gels, microemulsions, notably for biomedical uses. |