patent/US-5599659-A

http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5599659-A

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classificationCPCAdditional	http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-90
classificationCPCInventive	http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0226 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-069
classificationIPCInventive	http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N1-02
filingDate	1995-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate	1997-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor	http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e09c5f26a1188e05658a2bcb972f4223 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5024f715d0085af7075e08760a25245b
publicationDate	1997-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber	US-5599659-A
titleOfInvention	Preservation solution for ex vivo, warm preservation of tissues, explants,organs and vascular endothelial cells comprising retinal-derived fibroblast growth factor, cyclodextrin and chondroitin sulfate
abstract	The present invention is directed to a new hyperosmolar preservation solution useful in supporting the simultaneous in vitro growth of, and preservation of vascular endothelial cells from large vessel and microvessel origins. In addition, the preservation solution of the present invention may be used for initial flushing, and as a perfusate for storage of organs intended for transplantation using a warm preservation technology at between 18 DEG C. to 35 DEG C. Among the components of the preservation solution are colloid, mucopolysaccharide, retinal-derived fibroblast growth factor and a high magnesium concentration. Also, the present invention is directed to a method for preserving, without extreme hypothermia, an organ intended to be transplanted using the preservation solution.
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