| abstract |
A compound of the structure ##STR1## wherein R and R 1 are each, independently, ##STR2## or hydrogen; R 2 and R 3 are each, independently, alkyl, arylalkyl , or R 2 and R 3 may be taken together to form a cycloalkyl ring; n R 4 is a heterocyclic N-oxide radical, which may be optionally substituted; n R 5 is alkyl or arylalkyl; n R 6 and R 7 are taken together to form a saturated N-alkyl-heterocyclic N-oxide, which may be optionally substituted; n k=0-1, n m=0-1; n n=1-6; n with the proviso that R and R 1 are not both hydrogen, which is useful as an immunosuppressive, antiinflammatory, antifungal, antiproliferative, and antitumor agent. |