| abstract |
This invention relates to a method of effecting immunosuppression in a patient in need thereof comprising administering an effective amount of a compound of the formula (1) ##STR1## wherein the hydroxy substituent on the cyclopentenyl ring is in the CIS configuration relative to the bicyclic substituent, n Y 3 , Y 7 , Y 8 and Y 9 are each independently nitrogen or a CH group, n Q is NH 2 , halogen or hydrogen, and n Z is hydrogen, halogen, or NH 2 ; n or a pharmaceutically-acceptable salt thereof. |