patent/US-5453357-A

http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5453357-A

Outgoing Links

Predicate	Object
assignee	http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f79749e86afce9444a364ab60ca3584
classificationCPCAdditional	http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02
classificationCPCInventive	http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0606
classificationIPCInventive	http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735
filingDate	1992-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate	1995-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor	http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21485b04e3226fb9ccd6739d93503f29
publicationDate	1995-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber	US-5453357-A
titleOfInvention	Pluripotential embryonic stem cells and methods of making same
abstract	The present invention provides a non-mouse pluripotential embryonic stem cell which can: (a) be maintained on feeder layers for at least 20 passages; and (b) give rise to embryoid bodies and multiple differentiated cell phenotypes in monolayer culture. The invention further provides a method of making a pluripotential embryonic stem cell comprising administering a growth enhancing amount of basic fibroblast growth factor, leukemia inhibitory factor, membrane associated steel factor, and soluble steel factor to primordial germ cells under cell growth conditions, thereby making a pluripotential embryonic stem cell.
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