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filingDate 1992-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1995-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba885381c8fc9e21a8ee99bd236f3d58
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publicationDate 1995-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5385841-A
titleOfInvention PO438, a new calcium-regulated promoter
abstract There is disclosed a new calcium-regulated promoter to be used for increasing production of extracellular enzymes, or heterologous polypeptides, a recombinant vector that includes the DNA sequence of the promoter operatively linked to a DNA encoding said enzyme or polypeptide and a host organism transformed with the recombinant vector that includes the promoter operatively linked to the DNA encoding said enzyme or polypeptide. The present invention further relates to Streptomyces expression systems and methods for expressing foreign DNA sequences in Streptomyces and for secreting to the surrounding medium polypeptides and proteins coded for by those foreign DNA sequences.
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