http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5316932-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec3d7a9a543c4214ef75cdabb2d0e04b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4322cb4de342be2dbedcbe0c278f6f |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-814 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-803 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1007 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
filingDate | 1993-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1994-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d96064a86b078bcd76bf018fb814bb40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bfdca2389760fbb2f3c0faa1d10c7f5 |
publicationDate | 1994-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-5316932-A |
titleOfInvention | Homogeneous denatured human 06-guanine alkyltransferase prepared by immunoaffinity chromatography using monoclonal antibody specific for enzyme |
abstract | A denatured human O6-guanine alkyltransferase is disclosed. The enzyme is prepared by a process which involves denaturing the enzyme, contacting the denatured enzyme with a monoclonal antibody specific for the denatured enzyme on a substrate to which the monoclonal antibody is bound to, so that the denatured enzyme and the monoclonal antibody form an immunocomplex and then, eluting the denatured enzyme from the substrate-bound monoclonal antibody so that the denatured human O6-guanine alkyltransferase is obtained. The enzyme can be used to develop probes for the Mer- phenotype and these probes in turn are contemplated for use in identifying drug resistant tumors in patients. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7265248-B1 |
priorityDate | 1989-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.