abstract |
Compounds of general formula I: ##STR1## Wherein: R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 are variables. n These compounds have collagenase inhibition activity and are useful in the management of disease involving collagen degradation. Its uses include rheumatoide arthritis, corneal ulceration, osteoporosis, periodontitis, gingivitis and tumour invasion. |