| abstract |
New 11β-phenyl-14βH-steroids of general formula (I), where Z is an oxygen atom or the hydroxyimino-grouping N˜OH, and M and N are either jointly a second compound or L is a hydrogen atom and M is an α-permanent hydroxy group and either A and B together are a second compound and D is a hydrogen atom, where R 1 is a five or six-part heteroalkyl residue or a cycloalkyl, cycloalkenyl or aryl residue or A is a hydrogen atom and B and D together are a methylene bridge, where R 1 besides the aforementioned residues may be a possibly substituted hydrocarbon residue with up to 10 C atoms, a possibly substituted amino group, a hydroxy or C 1-8 alkoxy, mercapto or thioalkyl group, R 2 is a methyl or ethyl residue, and R 3 /R 4 represents the usual combination of substituents on the C17 atom in steroid chemistry, having antigestagenic and other properties. |