| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c9542186133097bd6bbb7d92393090 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-003 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-00 |
| filingDate |
1991-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1993-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7c2e5e56c04d270a815e1470eebd6f6 |
| publicationDate |
1993-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5219731-A |
| titleOfInvention |
Method for preparing optically-active amino acid derivatives |
| abstract |
The invention relates to a method for enzymatically producing directly optically-active amino acid derivatives in high optical purity from oxazolone precursors. Thus, such a precursor is subjected to the presence of a catalytically effective amount of a selected enzyme in a mutual solvent. The cyclic precursor is enantioselectively cleaved by hydrolysis. Subsequently, the desired optically-active amino acid derivative is recovered. A preferred cyclic precursor is a 5(4H)-oxazolone compound and a preferred enzyme is a lipase. Either aqueous or organic solvent media can be used. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6362209-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002169337-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9512573-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6180374-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5552317-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9400509-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03066873-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020143040-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8835676-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111132962-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111132962-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005176118-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6407281-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5994381-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2502896-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9517903-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9518627-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2401866-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5783427-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5449743-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5552318-A |
| priorityDate |
1991-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |