http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5190964-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da54f7ebbd2d9d8a82f92aca4d1b4e48 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-0083 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 |
filingDate | 1990-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1993-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b9d05fb4b598852a9b310752f43a5fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_186c9a341caf35ed6c11c719edfc5b7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58c2b760837325ed3292e0782a515f4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a079d6172a1fb1d237e73b48c4d11e63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cf93d6205cc6ebd813d55c9abece003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb7587a1a23b5049edea8184417123c3 |
publicationDate | 1993-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-5190964-A |
titleOfInvention | 5-fluorocarbacyclins, their preparation and pharmaceutical use |
abstract | 5-fluorocarbacyclin derivatives of the Formula I ##STR1## wherein R 1 is CH 2 OH or n A is --CH 2 --CH 2 --, trans --CH═CH-- or --C.tbd.C--, n W is a free or functionally modified hydroxymethylene group or free or functionally modified ##STR2## in which the OH group can be in the α-- or β-position, D is ##STR3## a C 1-10 -aliphatic group (e.g., alkyl or alkenyl) which optionally can be substituted by fluorine atoms, n n is 1, 2 or 3, n E is a direct bond, --C.tbd.C-- or --CR 6 .tbd.CR 7 -- in which R 6 represents a hydrogen atom or an alkyl group with 1-5 atoms and R 7 represents a hydrogen atom, a halogen atom or an alkyl group with 1-5 C atoms, n R 4 is alkyl, cycloalkyl or optionally substituted aryl or a heterocyclic group, n R 5 is a free or functionally modified hydroxy group n and, when R 2 is a hydrogen atom, its salts with physiologically compatible bases, n have valuable pharmacological properties. |
priorityDate | 1978-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 220.