| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56666880a5e2b7703e98a4f9b2d9daf6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-44 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-48 |
| filingDate |
1991-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1993-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71be0e7597065b65410354ec5439d26f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d22f0df95f2b38d643eebc6f76abbdfe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dce389dcb078a0befab55f95f976653
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37489a60019e4712bfa25cb678a3714b |
| publicationDate |
1993-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5179102-A |
| titleOfInvention |
Naphthyridinyl/naphthyridinylalkyl-n-terminal anino hydroxy β-amino acid derivatives |
| abstract |
Non-peptidyl compounds characterized generally as naphthyridinyl/naphthyridinylalkyl-N-terminal amino hydroxy beta -amino acid derivatives are useful as renin inhibitors for treatment of hypertension. Compounds of particular interest are of the formula <IMAGE> wherein R1 is selected from <IMAGE> wherein each of Y and Z is independently selected from hydrido, chloro, fluoro, methoxy and dimethylamino, wherein n is a number selected from zero through four, inclusive; wherein each of R2 and R4 is independently selected from hydrido and methyl; wherein R3 is methyl or ethyl; wherein R5 is cyclohexylmethyl; wherein R6 is hydroxy; and wherein R7 is isobutyl or ethyl; or a pharmaceutically-acceptable salt thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5442044-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5364844-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006252825-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005080141-A1 |
| priorityDate |
1989-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |