| abstract |
Arylmethylazoles of the formula I ##STR1## in which Aryl is (substituted) phenyl or naphthyl; n Z is CH or N; n R 1 and Q are H or alkyl; n R 2 is H, alk(en)yl or alkynyl; n R 3 and R 4 are H, alkyl or other hydrocarbons; or n R 3 and R 4 together are a--(CH 2 ) 2-11 chain or a bridged--(CH 2 ) 4-5 chain, n and their acid addition salts, stereoisomers and optically active enantiomers possess outstanding antimycotic and antidepressant activity. n They are obtained, inter alia, from arylmethylazoles II ##STR2## which are reacted with a strong base and then with a carbonyl compound III O═CR 3 R 4 ; thereafter, the product is reacted with the protic acid or with an alkyl halide IV R 2 Hal. n If desired, the products are converted to the acid addition salts, or the stereoisomers or optically active enantiomes are resolved. |