| abstract |
Benzoylguanidines of the formula I ##STR1## where R(1) or R(2) is equal to R(6)--S(O) n -- or R(7)R(8)N--O 2 S-- n and the other substituent R(1) or R(2) is in each case equal to H, F, Cl, Br, I, alkyl, alkoxy or phenoxy, R(6)--S(O) n or R(7)R(8)N-- n and R(6) is equal to alkyl, cycloalkyl, cyclopentylmethyl, cyclohexylmethyl or phenyl, n R(7) and R(8) are equal to alkyl or phenylakyl or phenyl, n and in which R(7) and R(8) may also together be a C 4 -C 7 chain, and in which R(7) and R(8), together with the nitrogen atom to which they are bonded, may be dihydroindole, tetrahydroquinoline or tetrahydroisoquinoline system, n and where R(3), R(4) and R(5) are equal to hydrogen or alkyl, or R(3) and R(4) are together an alkylene chain or R(4) and R(5) are together an alkylene chain, n and where n is equal to zero, 1 or 2 and their pharmaceutically tolerable salts are outstanding antiarrhythmics. |