abstract |
Mitomycin derivatives having the formula ##STR1## wherein X is acyl, lower alkyl, alkoxycarbonyl aryloxycarbonyl or aralkoxycarbonyl; n Y is hydrogen or methyl; n Z is hydrogen, methyl, acyl or allyloxycarbonyl; n one of R 1 and R 2 represents carbamoyloxymethyl and the other represents hydrogen, or R 1 and R 2 together represent methylene, show antibacterial and antitumor activities. |