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publicationNumber US-5011844-A
titleOfInvention Substituted 4-azatricyclo(22.3.1.04,9)octacos-18-ene derivatives, their preparation and pharmaceutical compositions containing them
abstract The compounds of formula I ##STR1## wherein either n R 1 is hydroxy, n R 2 is allyl or n-propyl and n there is a single bond between the carbon atoms numbered 14 and 15 n or n R 1 is missing, n R 2 is allyl and n there is a double bond between the carbon atoms numbered 14 and 15, n have interesting immunosuppressant and anti-inflammatory properties. n They are obtained by fermentation or synthesis, e.g. by hydrogenation or dehydration.
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