| abstract |
The present invention concerns compounds of the formula: <IMAGE> wherein R1 hydrogen, a hydroxyl group or a methoxy group; R2 is hydrogen or a methyl group; R3 is hydrogen or a methyl group; Y is a halogen, a secondary amino group or a tertiary amino group; and Z is hydrogen or a halogen. The invention further concerns pharmaceutical compositions which comprises the above-identified compound or the acid salts thereof, and the use of the compound or compositions for treating a malignancy in a subject. |