http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101941914-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aaadcd534c1edeab62f85ec7991cb759 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C221-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C225-24 |
filingDate | 2010-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_236f68a089a3a2319f3d59329fa69af5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03cf62830f86b0d2c146a15ade050a97 |
publicationDate | 2013-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-101941914-B |
titleOfInvention | Hydroxyl whole-protection didecyl quaternary ammonium with anti-tumor activity and preparation method thereof |
abstract | The invention relates to synthesis of an emodin derivant with an anti-tumor function, in particular to a hydroxyl whole-protection didecyl quaternary ammonium with anti-tumor activity and a preparation method thereof. The didecyl quaternary ammonium is decyldimethylchlorosilane-[2-(4,5,7-trimethoxy-9,10-anthraquinonyl)methyl]. The preparation method is characterized by taking emodin as a raw material to carry out a series of synthetic reaction. The emodin derivant of the invention has proliferation inhibition action of different degrees on liver cancer HepG2, gastric cancer BGC, neuroma SH-SY5Y, gastric cancer AGS, cervical cancer Hela and the like as well as normal human embryonic lung fibroblast HELP and can be used for preparing medicines for treating cancers. |
priorityDate | 2010-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.