| abstract |
A method of preventing or treating posttraumatic nervous injuries by administering a compound of the formula: ##STR1## wherein R 1 is hydrogen, a lower alkyl group, cyclohexyl or benzyl; Z is one of the groups ##STR2## if Z is a group (a), R 2 and R 3 together represent an additional bond between the carbon atoms bearing them, or if Z represents a group (b), R 2 is hydrogen; R 4 is hydrogen or lower alkyl; R 5 is hydrogen, lower alkyl or phenyl, and R 6 is hydrogen or methyl. Hydrates or pharmaceutically acceptable acid addition salts may also be used in the method. Pharmaceutical compositions used in this method containing such compounds in a prophylactically or therapeutically effective amount may be administered by infusion, injection, orally, perorally, rectally, percutaneously or other route. |