http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4874855-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20d3042eb4ea7c9afd525aa89373349d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-0053 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J51-00 |
| filingDate | 1988-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d75cf556d56eba8f0bf9722aada4e2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d68ad58fed50dab40475b24594f00d88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db585761d76d084740e481850ed77992 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2abdca20aa7b5547b46dd06f2cd551e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36668b6880798dca646b22d6e7bedd4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7771dab368f8c30f36a9089798a5bb76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ae0cae37694d63ade0762d3f2d06403 |
| publicationDate | 1989-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4874855-A |
| titleOfInvention | Steroid compounds and process of preparing the same |
| abstract | Disclosed are steroid compounds represented by general formula (I) ##STR1## wherein X and W together as >W-X represent a carbonyl group (>C═O) or a hydroxymethylene group (>CH(OH)), the hydroxy moiety of the hydroxymethylene group being of β-arrangement, and OR 1 and OR 2 independently represent an ester residue, and Y and Z together as --Y--Z-- represent a --(PpSe)CH--CH 2 -- group where Pp represent a phenyl group or a 2-pyridyl group, or Y and Z each represent an ethenylene group or a 1-bromoethylene group. n Also disclosed is a process of preparing the compound (I) includes reacting 6β, 9α-difluoro-5α,17α,21-trihydroxypregna-3,11,20-trione-17,21-diesters or 6β,9α-difluoro-5α,11β,17α,21-tetrahydroxypregna-3,20-dione-17,21-diesters as starting compound with an organic selenenyl halide selected from the group consisting of 2-pyridylselenenyl chloride, 2-pyridylselenenyl bromide, phenylselenenyl chlolride and phenylselenenyl bromide. n Further disclosed is a process of preparing 2-bromo-6β,9α-difluoro-11β,17α,21-trihydroxy-1,4-pregnadien-3,20-di-one-17,21-diester represented by general formula (VII) ##STR2## wherein OR 1 and OR 2 independently represent an ester residue, which comprises reacting with hydrogen chloride, or with thionyl chloride in the presence of a basic substance, the compound (V), and optionally reducing with a reducing agent when >W-X represents a carbonyl group. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3827747-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007035716-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4218718-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9961055-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010095940-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5725840-A |
| priorityDate | 1987-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 195.