| abstract |
Compounds of formula <IMAGE> wherein R is hydrogen atom or C1-C4 alkyl group optionally substituted from halogen atom or hydroxy group optionally protected, A is a Z, Z-O-C-O- or Z-C)- residue, wherein Z is phenylene, naphthylene, heterocyclediyl, C1-C7 alkylene, C2-C4 alkenylene, alkynylene, <IMAGE> C3-C8 cycloalkylene, aralkylene radical optionally substituted, and O(+) represents a group +NR1R2R3, wherein R1, R2 and R3 are each either: (i) a optionally substituted alkyl, aralkyl or aryl radical or (ii) R1 is as defined above under (i) and R2 and R3, taken together, represent an optionally substituted or fused heterocyclic radical, or (iii) R1, R2 and R3, taken together, represent an optionally substituted azonia-bicyclo or tricyclo radical, or (iv) R1, R2 and R3, taken together, represent an optionally substituted or fused pyridinium, pyrazinium, pyrazolium or pyridazinium radical, and the pharmaceutically or veterinarily acceptable salts thereof, are disclosed. A method of preparation is also provided. The compounds show high antibacterial activity. |