| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5be1d27acf8a63f82dff0177ddaf7fae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_087bed7abab91ae0f927879f9fe8b273 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-223
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6911
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5761
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-576
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-10 |
| filingDate |
1986-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1989-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea28a2d5bd6713f361fa00b3ffc2ee3b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b56445a198a64685c8aed9c352b7775 |
| publicationDate |
1989-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4861588-A |
| titleOfInvention |
Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers |
| abstract |
A hepatitis B vaccine containing a peptide with an amino acid chain of at least six consecutive amino acids within the pre-S gene coded region of the envelope of hepatitis B virus. The vaccine being free of an amino acid sequence corresponding to the naturally occurring envelope proteins of hepatitis B virus and a physiologically acceptable diluent. The peptide being free or linked to a carrier. The carrier being a conventional carrier or a novel carrier including a lipid vesicle stabilized by cross-linking and having covalently bonded active sites on the outer surface thereon. Such novel carrier being useful not only to link the novel peptide containing an amino acid chain with amino acids within the pre-S gene coded region of the surface antigen of hepatitis B virus, but can also be used to bind synthetic peptide analogues of other viral proteins, as well as bacterial, allergen and parasitic proteins of man and animals. The peptides of the invention can be utilized in diagnostics for the detection of antigens and antibodies. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5665710-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6020167-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6022543-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5804604-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5290562-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5980899-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5274081-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8679762-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6072049-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5747641-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9105059-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003235591-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03037265-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5736378-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5871747-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003215788-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6068981-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9002176-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6117653-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6110706-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6100065-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6346375-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6316003-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5576175-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5147652-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008193916-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002032307-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5670617-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9917747-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5674980-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5652122-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9117768-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6589530-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03037265-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5340575-A |
| priorityDate |
1985-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |